When the female American cockroach belched, more than an hour had passed since the roaches first nibbled on the gel bait.

Therefore, besides this unlucky one, the first batch of roaches that ate the gel bait also began to react one after another.

At this time, in containers 1-3, one could clearly see several clusters of roaches, rustling and having a wild party.

In stark contrast to this, was the scene in containers 4-6:

More than forty minutes had passed, and even in the best-performing container 4, only five or six roaches had become excited.

Another hour passed.

In container 2, the males that had eaten the female roaches also began to show abnormalities one after another.

At the same time, due to the diffusion of pheromones, each male roach was surrounded by several females, forcing it to perform an indescribable act.

The male roaches died in brutal exploitation, and their bodies became food for the female roaches. The bloody scene was so brutal that even Cheng Ge in heaven would exclaim and feel glad that he died early.

Then, these female roaches dispersed one after another, and the cycle of transmission began again.

Eight hours later.

In containers 1-3, only a few roaches still showed signs of life, the rest were either incomplete corpses or had completely died.

In container 4, there were only about ten roach corpses, and the number of roaches in an excited state of poisoning was about fifteen or sixteen.

As for containers 5 and 6, the number of deaths was in single digits.

Seeing this, Tang Yiqiu, the youngest among them, couldn't suppress her emotions and cheered:

"Senior, it seems our experiment was very successful!"

As a senior student, this was her first time participating in a project of this level. Seeing the results of the research group, how could this young girl not be excited?

However, to her surprise, Xu Yun gently shook his head:

"Successful? Little Tang, this is not yet a success. We have developed the fourth generation of Fipronil, but is it really the perfect form of Fipronil?"

Seeing that his junior was a bit confused, Xu Yun pointed to the biological container and said:

"I ask you, what did the roaches that ate the corpses of their own kind do during the experiment?"

Tang Yiqiu blinked in confusion and subconsciously answered:

"They became excited, then released pheromones and mated with roaches of the opposite sex."

"You see, isn't that the problem?"

Xu Yun clapped his hands and laughed:

"The volume of our biological containers is limited, which led to all the roaches inside being covered by pheromones and then engaging in mating behavior.

But in the natural environment, the activity range of roaches is far more than this small container, isn't it?

Their biological density may not be comparable to that in the container, but the complexity of their travel routes and the crossing of smells is much higher than in the container. This is the difference between the experimental environment and the real environment."

Tang Yiqiu nodded in understanding, her ponytail swinging behind her, and asked:

"So, Senior Xu, are you planning to improve the pheromone protein to increase the spread of pheromones?"

"No, no, no, you misunderstood my meaning."

Xu Yun shook his head quickly and said:

"What I mean is...

According to our current Fipronil formula, if a male roach A only attracts a female B before it dies, what if a male or several males C pass by at this time?

With good luck, C might wait for B to mate with A and then be attracted by B's pheromones, and then mate with B and get poisoned.

But the onset of the drug takes time, what if C leaves during the incubation period of the drug?

Wouldn't this possibly lead to a significant portion of the targets not being covered?"

Looking at the stunned faces of Tang Yiqiu and others, Xu Yun laughed happily:

"So... can we add a kind of lure to the pheromone protein, so that the pheromones released by the roaches that eat for the first time do not distinguish between males and females, so that A can attract C, that is...

Same-sex mating, or exchanging lymph fluid?"

After Xu Yun finished speaking, the entire laboratory fell silent.

After a few seconds, Tang Yiqiu and Zhou Peiyao both exclaimed in unison:

Explore the extended edition on pawread dot com.

"Senior, are you a devil?!"

Xu Yun shook his head and explained seriously:

"No, no, no, I'm just making a logical supplement from a realistic perspective.

After all, we have a biological model as a basis—a standard residential area of one kilometer, the daily interaction times of same-sex roaches is only 0.37 times.

So the situation I mentioned is very likely to happen in reality.

Moreover, if we can solve the problem of same-sex lures, we may even be able to develop corresponding insecticides for mosquitoes and flies in the future, which is a very broad space."

Xu Yun spoke with great confidence, because one of the core points of the fifth-generation Fipronil formula he obtained was that it could produce specific lures through cell receptors, causing the roaches' cognition to be confused and mate with males.

Of course.

There were also a bit of personal emotions involved, but let's not mention that for now.

Then Xu Yun paused and said seriously:"Lastly, there's the issue of pest extermination efficiency. Although our fourth-generation Bichongzine is faster than the other three types of gel baits, I still think the binding speed to the target protein is a bit slow.

Considering the attraction effect generated by the movement of living organisms, I personally think that the first-generation should take 20 minutes, and the second to fifth generations should take an hour. This should be a reasonable configuration.

After all, cockroaches are attracted to feed on their dead kind."

Previously, considering that the research team had not yet successfully developed the fourth-generation Bichongzine, Xu Yun withheld some optimization directions for the fifth-generation Bichongzine.

After all, talking about the fifth generation without breaking through the fourth seemed a bit overly ambitious.

However, now with the technological breakthrough of the fourth-generation Bichongzine, some of his ideas can be brought to the table:

"For example, the target of Bichongzine is nAchR, specifically the R81 arginine residue in the LoopD region of the β1 subunit. The binding time generally won't be less than thirty minutes.

So...

Can we supplement some other ideas?

Like inhibiting acetylcholinesterase, or acting on the sodium channel?"

Looking at the people lost in thought, Xu Yun continued:

"Mammalian sodium channels have 9 subtypes, that is, NaV1.1-NaV1.9. The subtypes in insects are a bit more complex, and the binding mode of the receptor also needs our deduction."

"But we've already crossed the most difficult threshold of cyclization. The remaining steps will undoubtedly be much easier. So everyone, let's push a little harder?"

"Let's strive to make the cockroaches 'man up' as soon as possible, and ascend to heaven!"